OTHER ENDOCRINE TISSUES AND HORMONES
DUODENUM
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AUTOCRINE AND PARACRINE SUBSTANCES
ADIPOSE TISSUES
DUODENUM
THE STOMACH
THE UTERUS
THE PLACENTA
THE KIDNEYS
THE THYMUS
PINEAL GLAND
THE HEART

ENTEROENDOCRINE CELLS IN THE DUODENUM PRODUCE A NUMBER OF HORMONES

SECRETIN WAS THE FIRST HORMONE TO BE DISCOVERED.  IT CAUSES THE SECRETION OF A BICARBONATE RICH SECRETION FROM THE PANCREAS, INCREASES INTESTINAL SECRETIONS, STIMULATES THE SECRETION OF BILE BY THE LIVER AND INHIBITS GASTRIC SECRETIONS UNDER CERTAIN CONDITIONS.

CHOLECYSTOKININ (CCK) IS SECRETED BY ENTEROENDOCRINE CELLS IN THE DUODENAL WALL.  IT  STIMULATES GALL BLADDER CONTRACTION, MOVING BILE INTO THE DUODENUM.  IT ALSO STIMULATES THE SECRETION OF ENZYME RICH DIGESTIVE JUICE FROM THE PANCREAS. IT CAUSES RELAXATION OF THE HEPATOPANCREATIC SPHINCTER AND ALSO CAN INHIBIT GASTRIC SECRETIONS UNDER CERTAIN CONDITIONS.
 
GASTRIN IS ALSO PRODUCED BY THE DUODENUM.  IT INCREASES GASTRIC SECRETION AND EMPTYING BY INCREASING GASTRIC MOTILITY AND RELAXING THE PYLORIC SPHINCTER.
 
GASTRIC INHIBITORY PEPTIDE IS PRODUCED BY THE DUODENUM AND THE PROXIMAL PORTIONS OF THE JEJUNUM.  IT INHIBITS GASTIC SECRETIONS AND DECREASES GASTRIC MOTILITY.
 

GASTRIC INHIBITORY PEPTIDE  IS SECRETED BY THE EPITHELIAL CELLS OF THE DUODENUM.  IT INHIBITS GASTRIC MOTILITY AND THE SECRETION OF HCL BY THE STOMACH.  
 
GIP IS SOMETIMES CALLED GLUCOSE DEPENDENT INSULINOTROPIC PEPTIDE BECAUSE IT ENHANCES THE SECRETION OF INSULIN.